CARBAPENEM COMPOUNDS

This invention relates to carbapenem compounds of the following formula:wherein A, Z, X, R1, and R4 are as described herein, as well as stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bac...

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Main Authors PERIASAMY, Hariharan, DONG, Shuzhi, BALASUBRAMANIAN, Gopalan, PAUL-SATYASEELA, Maneesh, SRINIVASAN, Chidambaram, Venkateswaran, SINGH, Sheo, YOUNG, Katherine, THIRUNAVUKKARASU, Bharani, DESHKUMAR, Manjula, Devi, IYER, Sridhar, Ramanathan, GUNTURU, Prabhakar, Rao, MILLER, Michael, PARAMESWARAN, Venkatesan, WANG, Hongwu, JAKKALA, Venkateshwarlu, NARGUND, Ravi, P
Format Patent
LanguageEnglish
French
German
Published 23.01.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to carbapenem compounds of the following formula:wherein A, Z, X, R1, and R4 are as described herein, as well as stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
Bibliography:Application Number: EP20170724297