THERAPEUTIC ANTIBODIES
The present invention concerns human antibodies recognizing the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signaling, whereby the pro- inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to th...
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Main Authors | , , , , |
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Format | Patent |
Language | English French German |
Published |
09.01.2019
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention concerns human antibodies recognizing the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signaling, whereby the pro- inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders. |
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Bibliography: | Application Number: EP20180175085 |