A COMPOSITION FOR USE IN A METHOD FOR PREVENTION OR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS

The present disclosure provides a new microbicide pharmaceutical composition for topical pre-exposure prophylaxis or topical post-exposure prophylaxis. The present disclosure relates to the incorporation of nanoparticles loaded with different antiretroviral compounds in soft and flexible vaginal fil...

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Main Authors DOS SANTOS CUNHA REIS, Cassilda Maria, CARMELINO CARDOSO SARMENTO, Bruno Filipe, GONÇALVES DAS NEVES, José Alberto, MEIRA MACHADO, Fátima Alexandra
Format Patent
LanguageEnglish
French
German
Published 12.09.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure provides a new microbicide pharmaceutical composition for topical pre-exposure prophylaxis or topical post-exposure prophylaxis. The present disclosure relates to the incorporation of nanoparticles loaded with different antiretroviral compounds in soft and flexible vaginal films. Antiretroviral compounds may be present in films either as single agent or in combination with nanoparticles. Antiretroviral-loaded nanoparticles-in-vaginal films are to be administered in the vagina around the time of sexual intercourse in order to prevent the sexual transmission of HIV.
Bibliography:Application Number: EP20160819358