NUCLEIC ACID DERIVATIVE HAVING IMMUNOSTIMULATORY ACTIVITY
The purpose of the present invention is to provide double-stranded oligonucleotides comprising the CpG oligonucleotide mentioned below, as a nucleic acid derivative having an immunostimulatory activity. An adjuvant comprising a double-stranded oligonucleotide, wherein a first strand is a CpG oligonu...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French German |
Published |
08.08.2018
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Subjects | |
Online Access | Get full text |
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Summary: | The purpose of the present invention is to provide double-stranded oligonucleotides comprising the CpG oligonucleotide mentioned below, as a nucleic acid derivative having an immunostimulatory activity. An adjuvant comprising a double-stranded oligonucleotide, wherein
a first strand is a CpG oligonucleotide consisting of 8 to 50 nucleotides,
a second strand is an oligonucleotide consisting of 8 to 60 nucleotides and comprising a sequence capable of hybridizing with the first strand, and a lipid binds to the second strand through a linker or without a linker. |
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Bibliography: | Application Number: EP20160851711 |