HOST CELLS FOR PREPARING ADIPATE (ESTER OR THIOESTER)

This invention provides a host cell comprising nucleic acid sequences encoding an enzyme converting a 2,3-dehydroadipate ester or 2,3-dehydroadipate thioester into an adipate ester or thioester, an enzyme converting a 3-hydroxyadipate ester or 3-hydroxyadipate thioester into the 2,3-dehydroadipatees...

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Bibliographic Details
Main Authors Trefzer, Axel Christoph, Van Den Berg, Marco Alexander, Wu, Liang, De Wildeman, Stefaan Marie André
Format Patent
LanguageEnglish
French
German
Published 11.07.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:This invention provides a host cell comprising nucleic acid sequences encoding an enzyme converting a 2,3-dehydroadipate ester or 2,3-dehydroadipate thioester into an adipate ester or thioester, an enzyme converting a 3-hydroxyadipate ester or 3-hydroxyadipate thioester into the 2,3-dehydroadipateester or 2,3-dehydroadipate thioester, an enzyme converting a 3-oxoadipate ester or 3-oxoadipate thioester into the 3-hydroxyadipate ester or thioester; and an enzyme reacting a succinate ester or succinate thioester with an acetate ester or acetate thioester and generating the 3-oxoadipate ester or 3-oxoadipate thioester.
Bibliography:Application Number: EP20170202553