BICYCLIC HETEROCYCLES AS INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN
The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2, D3, X, Y, A1, A2, R1, R5 and the subscript a are as described herein. The compounds are CETP inhibitors and are useful for raising FIDL-cholesterol, reduc...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | English French German |
| Published |
23.05.2018
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| Abstract | The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2, D3, X, Y, A1, A2, R1, R5 and the subscript a are as described herein. The compounds are CETP inhibitors and are useful for raising FIDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: |
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| AbstractList | The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2, D3, X, Y, A1, A2, R1, R5 and the subscript a are as described herein. The compounds are CETP inhibitors and are useful for raising FIDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: |
| Author | SHAO, Pengcheng Patrick KATIPALLY, Revathi Reddy THATAI, Jayanth Thiruvellore VACHAL, Petr SARKAR, Sujit Kumar |
| Author_xml | – fullname: THATAI, Jayanth Thiruvellore – fullname: VACHAL, Petr – fullname: SHAO, Pengcheng Patrick – fullname: SARKAR, Sujit Kumar – fullname: KATIPALLY, Revathi Reddy |
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| DocumentTitleAlternate | HÉTÉROCYCLES BICYCLIQUES EN TANT QU'INHIBITEURS DE LA PROTÉINE DE TRANSFERT DES ESTERS DE CHOLESTÉROL BICYCLISCHE HETEROCYCLEN ALS INHIBITOREN DES CHOLESTERINESTERTRANSFERPROTEINS |
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| Notes | Application Number: EP20160824927 |
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| PublicationDateYYYYMMDD | 2018-05-23 |
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| PublicationYear | 2018 |
| RelatedCompanies | Merck Sharp & Dohme Corp |
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| Snippet | The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2, D3, X, Y, A1,... |
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| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | BICYCLIC HETEROCYCLES AS INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN |
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