VACCINE COMPOSITIONS AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME AND PORCINE CIRCOVIRUS ASSOCIATED DISEASES

A fusion protein comprising an antigen-presenting cell (APC)-binding domain or a CD91 receptor-binding domain, a translocation peptide, a fusion antigen, an endoplasmic reticulum retention sequence, and optionally a nuclear export signal is disclosed. The fusion antigen comprises a porcine reproduct...

Full description

Saved in:
Bibliographic Details
Main Authors CHIEN, Yu-Hsin, CHANG, Hsiu-Kang, TSAI, Meng-Ju, CHOU, Wei-I, LAI, Pao-Yen
Format Patent
LanguageEnglish
French
German
Published 11.04.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:A fusion protein comprising an antigen-presenting cell (APC)-binding domain or a CD91 receptor-binding domain, a translocation peptide, a fusion antigen, an endoplasmic reticulum retention sequence, and optionally a nuclear export signal is disclosed. The fusion antigen comprises a porcine reproductive and respiratory syndrome virus (PRRSV) ORF7 antigen, a PRRSV ORF1b antigen, a PRRSV ORF6 antigen, and a PRRSV ORF5 antigen. The fusion protein is useful for inducing antigen-specific cell-mediated and humoral responses.
Bibliography:Application Number: EP20160804176