TWO CONOTOXIN PEPTIDES, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF

Provided are two novel conotoxin peptides, namely É-CPTx-btl1 and É-CPTx-btl2, amino acid sequences thereof being shown as SEQ ID NO: 1 or 2 respectively. Also provided are polynucleotides coding these two peptides, constructs, expression vectors and transformed cells containing the polynucleotides,...

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Bibliographic Details
Main Authors WEN, Bo, LIU, Jie, LIN, Zhilong, TONG, Ting, MO, Fen
Format Patent
LanguageEnglish
French
German
Published 28.02.2018
Subjects
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Summary:Provided are two novel conotoxin peptides, namely É-CPTx-btl1 and É-CPTx-btl2, amino acid sequences thereof being shown as SEQ ID NO: 1 or 2 respectively. Also provided are polynucleotides coding these two peptides, constructs, expression vectors and transformed cells containing the polynucleotides, and preparation methods for the two peptides. The conotoxin peptides can be applied to treatment of calcium ion channel-related diseases.
Bibliography:Application Number: EP20150889516