DOSAGE REGIMEN FOR MADCAM ANTAGONISTS

The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

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Bibliographic Details
Main Authors HASSAN-ZAHRAEE, Mina, ZHANG, Weidong, TILLEY, Mera Krishnan, PRADHAN, Vivekananda, COMER, Gail M, VINCENT, Michael Steven, BANERJEE, Anindita, CATALDI, Fabio, PAGE, Karen Michelle, AHMAD, Alaa, CLARE, Robert A, VON SCHACK, David J
Format Patent
LanguageEnglish
French
German
Published 27.07.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.
Bibliography:Application Number: EP20160702586