METHOD OF PREPARING DIFLUORINATED ALCOHOL COMPOUND

A method of preparing a difluorinated alcohol compound is provided. The difluorinated alcohol compound can be easily synthesized when an aldehyde and N-fluorobenzenesulfonimide are reacted in the presence of L-proline, and thus the method has advantage in that preparation processes are simple and re...

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Bibliographic Details
Main Authors Kwon, Da Eun, Hong, Myeng Chan, Kwag, Chong Yun
Format Patent
LanguageEnglish
French
German
Published 29.01.2020
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:A method of preparing a difluorinated alcohol compound is provided. The difluorinated alcohol compound can be easily synthesized when an aldehyde and N-fluorobenzenesulfonimide are reacted in the presence of L-proline, and thus the method has advantage in that preparation processes are simple and reagents are economical and safe, compared to the related-art methods. Therefore, the preparation method can be effectively applied to prepare a difluorinated alcohol used in various applications for raw materials such as functional medicines, agricultural chemicals, polymerizable compounds, etc.
Bibliography:Application Number: EP20160189248