PHARMACEUTICAL TABLET COMPOSITION

The object of the present invention is a pharmaceutical tablet composition comprising an NSAID and a PPI and having improved stability and bioavailability. The present invention relates to a pharmaceutical tablet composition comprising: a) a multilayer tablet core comprising: i) a non-steroidal anti...

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Bibliographic Details
Main Authors STANGELJ, Veronika, PAVLIN, Darja, SLANC-VOVK, Janika, VRECER, Franc, SIMONCIC, Kristina Debeljak, HUDOVORNIK, Grega, KUKEC, Simon, SKUBE, Maja Kincl
Format Patent
LanguageEnglish
French
German
Published 01.11.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The object of the present invention is a pharmaceutical tablet composition comprising an NSAID and a PPI and having improved stability and bioavailability. The present invention relates to a pharmaceutical tablet composition comprising: a) a multilayer tablet core comprising: i) a non-steroidal anti- inflammatory drug (NSAID) layer comprising an NSAID and at least one pharmaceutically acceptable excipient; ii) an optional middle layer; iii) a proton pump inhibitor (PPI) layer comprising multiple units of PPI coated with a protective coating; b) a barrier coating surrounding the multilayer tablet core; and c) a gastro-resistant coating surrounding the barrier coating.
Bibliography:Application Number: EP20150820858