HYDROXY CONTAINING FXR (NR1H4) MODULATING COMPOUNDS

The present invention relates to compounds of formula (1) which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear r...

Full description

Saved in:
Bibliographic Details
Main Authors KINZEL, Olaf, GEGE, Christian, SCHMITT, Aaron C, KREMOSER, Claus
Format Patent
LanguageEnglish
French
German
Published 03.04.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to compounds of formula (1) which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
Bibliography:Application Number: EP20150816665