PHARMACEUTICAL COMPOSITION COMPRISING PLASMINOGEN AND USES THEREOF

Pharmaceutical compositions comprising plasminogen or a biologically active variant thereof are disclosed. In an embodiment, the composition comprises a tonicity modifier, a bulking agent, and a stabilising agent and has a pH of about 3.0 to about 10.0. In another embodiment, the composition contain...

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Bibliographic Details
Main Authors PLUM, Stacy, GARZON-RODRIGUEZ, William, BLACKMAN, Davida, YU, Betty, ROBITAILLE, Martin
Format Patent
LanguageEnglish
French
German
Published 27.06.2018
Subjects
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Summary:Pharmaceutical compositions comprising plasminogen or a biologically active variant thereof are disclosed. In an embodiment, the composition comprises a tonicity modifier, a bulking agent, and a stabilising agent and has a pH of about 3.0 to about 10.0. In another embodiment, the composition contains an amount of particles in suspension equal to or greater than 10 μm which is lower than 6000 particles per 100 ml, and preferably lower than 2000 particles per 100 ml. Uses of these compositions as a medicament is contemplated. Various therapeutic uses of these pharmaceutical compositions is also contemplated.
Bibliography:Application Number: EP20150868755