METHOD OF REMOVING DNA FROM BIOTECHNOLOGICAL PRODUCTS

The present invention relates to a method for degrading DNA in a sample obtained by microbial fermentation or biotransformation, comprising treating the sample with a combination of increased temperature and low pH. It also relates to a method for releasing DNA from a microbial cell, comprising incu...

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Bibliographic Details
Main Authors HAEFNER, Stefan, HOFF, Birgit, JEONG, Weol Kyu, SCHOLTEN, Edzard
Format Patent
LanguageEnglish
French
German
Published 29.11.2023
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Summary:The present invention relates to a method for degrading DNA in a sample obtained by microbial fermentation or biotransformation, comprising treating the sample with a combination of increased temperature and low pH. It also relates to a method for releasing DNA from a microbial cell, comprising incubating the microbial cell at a temperature of 45° C. to 55° C. for two to ten hours. Finally, the present invention provides a method for producing a product, comprising a step of releasing DNA from a microbial cell and degrading said DNA.
Bibliography:Application Number: EP20150817104