METHOD FOR PRODUCING CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND STABLE LYOPHILIZED PREPARATION
The objects of the present invention are to provide a process for producing crystals of compound (I) easily in an industrial scale, and a stable lyophilized composition of compound (I). It has been found that subjecting an aqueous solution containing compound (I) and an inorganic salt such as sodium...
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Main Authors | , , , , |
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Format | Patent |
Language | English French German |
Published |
02.09.2020
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Subjects | |
Online Access | Get full text |
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Summary: | The objects of the present invention are to provide a process for producing crystals of compound (I) easily in an industrial scale, and a stable lyophilized composition of compound (I). It has been found that subjecting an aqueous solution containing compound (I) and an inorganic salt such as sodium chloride to lyophilization yields a lyophilized composition having good storage stability wherein the compound (I) is crystalline, and further that crystals of compound (I) can be obtained from said aqueous solution without lyophilization. |
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Bibliography: | Application Number: EP20150866317 |