ANTIBODIES THAT BIND AND BLOCK TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS-1 (TREM-1)

There is provided antibodies that are capable of specifically binding TREM-1 and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages, and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease.

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Bibliographic Details
Main Authors WIBERG, Charlotte, PADKJÆR, Søren, STENNICKE, Vibeke Westphal, SALBO, Rune, GRELL, Susanne Nedergaard, READ, Christine Brender, HENRIKSEN, Anette
Format Patent
LanguageEnglish
French
German
Published 31.07.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is provided antibodies that are capable of specifically binding TREM-1 and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages, and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease.
Bibliography:Application Number: EP20170156557