COSTIMULATORY CHIMERIC ANTIGEN RECEPTOR T CELLS TARGETING IL13R 2

Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13Ra2 (IL13Ra2), a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.

Saved in:
Bibliographic Details
Main Authors FORMAN, Stephen J, BROWN, Christine E
Format Patent
LanguageEnglish
French
German
Published 22.05.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13Ra2 (IL13Ra2), a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
Bibliography:Application Number: EP20150775539