PHENYL QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS

The invention relates to methods of reducing the level of 2-hydroxyglutarate in cells by administration of an inhibitor of mutant isocitrate dehydrogenase-1.

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Bibliographic Details
Main Authors LANCIA, Jr., David R, LIN, Jian, CARAVELLA, Justin Andrew, DIEBOLD, R. Bruce, ERICSSON, Anna, LU, Wei, WANG, Zhongguo, GUSTAFSON, Gary, ASHWELL, Susan, CAMPBELL, Ann-Marie
Format Patent
LanguageEnglish
French
German
Published 21.11.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to methods of reducing the level of 2-hydroxyglutarate in cells by administration of an inhibitor of mutant isocitrate dehydrogenase-1.
Bibliography:Application Number: EP20150771464