LACTOBACILLUS PLANTARUM INDUCIA STRAIN DSM 21379 AS HYPOCHOLESTEROLEMIC AGENT AND ANTIMICROBIAL AGENT AGAINST CLOSTRIDIUM DIFFICILE

• Main Authors: KÕLJALG, Siiri, SMIDT, Imbi, RÄTSEP, Merle, STSEPETOVA, Jelena, MIKELSAAR, Raik-Hiio, TRUUSALU, Kai, SEPP, Epp, MIKELSAAR, Marika, SONGISEPP, Epp, VALLAS, Mirjam, HÜTE, Pirje, KILK, Kalle
• Format: Patent
• Language: English; French; German
• Published: 15.04.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A microorganism strain Lactobacillus plantarum Inducia DSM 21379 for use as hypocholesterolemic, antimicrobial and anti-oxidative agent and as enhancer of the natural defense potential of a subject. L. plantarum Inducia is used for reducing the level of LDL-cholesterol in blood for preventing the cholesterol metabolism disorders and cardiovascular disorders. L. plantarum Inducia enhances simultaneously the natural defense potential and cellular immunity, and as anti-oxidative agent enhances anti-oxidative activity of blood by reducing the level of oxidized low density lipoprotein (ox-LDL). The strain is also used as an antimicrobial agent for lowering risk of Clostridium difficile associated diarrhea (CDAD) by preventing germination of C. difficile spores and by suppressing proliferation of its vegetative cells. The compositions comprising L. plantarum Inducia decrease the levels of LDL-cholesterol and ox-LDL in blood, enhance the natural defense potential and lower risk of CDAD. The composition may further comprise xylitol.