MONOCYCLIC ISOXAZOLINES AS INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN

Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein Dl, D2 and D3 are each N, CH, or substituted CH, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis...

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Bibliographic Details
Main Authors THATAI, Jayanth Thiruvellore, VACHAL, Petr, SHAO, Pengcheng Patrick, YE, Feng
Format Patent
LanguageEnglish
French
German
Published 23.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein Dl, D2 and D3 are each N, CH, or substituted CH, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis.
Bibliography:Application Number: EP20150827553