METHODS OF INCREASING MUSCLE MASS USING NON-TOXIC TETANUS TOXIN C FRAGMENT (TTC)

The present disclosure relates to the use of the non-toxic proteolytic C fragment of tetanus toxin and plasmids encoding such protein fragment to increase muscle mass and/or muscle strength in a subject in need thereof. As such, methods of ameliorating the severity of a pathological condition charac...

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Bibliographic Details
Main Authors ORTIZ SAGRISTA, Jordi, ZARAGOZA FRNANDEZ, Pilar, BOSSER ARTAL, Ramon, OSTA PINZOLAS, Rosario, MUNOZ GONZALVO, Maria Jesus, CALVO ROYO, Ana Cristina, MORENO MARTINEZ, Laura
Format Patent
LanguageEnglish
French
German
Published 10.05.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure relates to the use of the non-toxic proteolytic C fragment of tetanus toxin and plasmids encoding such protein fragment to increase muscle mass and/or muscle strength in a subject in need thereof. As such, methods of ameliorating the severity of a pathological condition characterized, at least in part, by a decreased amount, development, or metabolic activity of muscle are provided. The disclosed compositions and method are also useful for the treatment of condition in which increase in muscle mass and muscle strength are desirable, including cosmetic uses.
Bibliography:Application Number: EP20150787666