LIVE ATTENUATED AFRICAN HORSESICKNESS VIRUS

The present invention relates to a live attenuated African horsesickness virus, (family Reoviridae, genus Orbivirus), a method of producing and using such a virus, a vaccine and an immunisation kit including such a virus; in which the genome of the virus has been altered such that the expression of...

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Bibliographic Details
Main Authors WRIGHT, Isabella, Maria, POTGIETER, Abraham, Christiaan, ERASMUS, Balthasar, Johannes
Format Patent
LanguageEnglish
French
German
Published 05.04.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a live attenuated African horsesickness virus, (family Reoviridae, genus Orbivirus), a method of producing and using such a virus, a vaccine and an immunisation kit including such a virus; in which the genome of the virus has been altered such that the expression of the non-structural protein 4 (NS4) as a wild type or complete protein is eliminated.
Bibliography:Application Number: EP20150798229