METHOD FOR PRODUCING PANCREATIC BLAST CELLS AND PANCREATIC DISEASE TREATMENT AGENT CONTAINING PANCREATIC BLAST CELLS

Provided is a method for generating pancreatic bud cells, having the step of culturing PDX1 + /NKX6.1 - cells in a medium containing KGF, EGF and a BMP inhibitor. The culturing step may be performed in suspension cultures or in adherent cultures. When the cells are cultured in adherent cultures, the...

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Bibliographic Details
Main Authors TOYODA, Taro, OSAFUNE, Kenji
Format Patent
LanguageEnglish
French
German
Published 29.03.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Provided is a method for generating pancreatic bud cells, having the step of culturing PDX1 + /NKX6.1 - cells in a medium containing KGF, EGF and a BMP inhibitor. The culturing step may be performed in suspension cultures or in adherent cultures. When the cells are cultured in adherent cultures, the cells may be cultured in a medium further containing a ROCK inhibitor or a nonmuscle myosin II inhibitor.
Bibliography:Application Number: EP20150795700