INHIBITORS OF THE WNT SIGNALLING PATHWAYS

The present invention relates to inhibitors of the Wnt signalling pathways of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said co...

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Main Authors MÖNNING, Ursula, SCOTT, William, PUEHLER, Florian, ZORN, Ludwig, BASTING, Daniel, SIEGEL, Franziska, LIU, Ningshu, MÖWES, Manfred, SCHNEIDER, Dirk, THEDE, Kai, BENDER, Eckhard, GIESE, Anja, LIENAU, Philip, HÄGEBARTH, Andrea, GOLZ, Stefan, GEISLER, Jens
Format Patent
LanguageEnglish
French
German
Published 25.01.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to inhibitors of the Wnt signalling pathways of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper- proliferative disorder, as a sole agent or in combination with other active ingredients.
Bibliography:Application Number: EP20150710498