SPECIFIC ACTIVATION OF A REGULATORY T CELL AND ITS USE FOR TREATMENT OF ASTHMA, ALLERGIC DISEASE, AUTOIMMUNE DISEASE, GRAFT REJECTION AND FOR TOLERANCE INDUCTION

The present invention relates to a Treg cell activator for regulatory (Treg) cell activation via interaction with a Treg cell epitope as set forth in SEQ ID NO:1 which is HIV-1 gp120, or HIV-1 gp120 derived fragments, peptides or polypeptides thereof comprising an amino acid sequence as set forth in...

Full description

Saved in:
Bibliographic Details
Main Authors SCHNEIDER, Franz-Josef, SCHMITT, Edgar, BECKER, Christian, JONULEIT, Helmut, BOPP, Tobias
Format Patent
LanguageEnglish
French
German
Published 29.07.2020
Subjects
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to a Treg cell activator for regulatory (Treg) cell activation via interaction with a Treg cell epitope as set forth in SEQ ID NO:1 which is HIV-1 gp120, or HIV-1 gp120 derived fragments, peptides or polypeptides thereof comprising an amino acid sequence as set forth in SEQ ID NO.: 3, SEQ ID NO.: 4, SEQ ID NO.: 5, SEQ ID NO.: 6, SEQ ID NO.: 7, SEQ ID NO.: 8, SEQ ID NO.: 9, or SEQ ID NO.: 10 for use in a method for the prevention or treatment of a disease, which is characterized in that its clinical picture is influenced positively by an increase of activated Treg cells in response to the Treg cell activator.
Bibliography:Application Number: EP20160166807