SPR-BASED BRIDGING ASSAY FOR DETERMINING THE BIOLOGICAL ACTIVITY OF MULTIVALENT, MULTISPECIFIC MOLECULES

Herein is reported the use of a binding assay of a bivalent, bispecific antibody that has the smaller kD value (dissociation constant) for the interaction with its antigen for the immobilization of the bivalent, bispecific antibody to a solid surface for the determination of the biological activity...

Full description

Saved in:
Bibliographic Details
Main Authors GASSNER, CHRISTIAN, MOELLEKEN, JOERG, PAPADIMITRIOU, APOLLON, KETTENBERGER, HUBERT, REGULA, JOERG THOMAS
Format Patent
LanguageEnglish
French
German
Published 19.10.2016
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
Online AccessGet full text

Cover

More Information
Summary:Herein is reported the use of a binding assay of a bivalent, bispecific antibody that has the smaller kD value (dissociation constant) for the interaction with its antigen for the immobilization of the bivalent, bispecific antibody to a solid surface for the determination of the biological activity of the bivalent, bispecific antibody.
Bibliography:Application Number: EP20140812183