DETECTION OF NUCLEIC ACIDS BY STRAND INVASION BASED AMPLIFICATION
A method for detecting a target nucleic acid sequence in a sample in the presence of at least protein capable of binding to single-stranded DNA is provided, comprising contacting said sample with at least one oligonucleotide probe comprising a fluorophore, a quencher and a region complementary to sa...
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Main Authors | , |
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Format | Patent |
Language | English French German |
Published |
31.10.2018
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Subjects | |
Online Access | Get full text |
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Summary: | A method for detecting a target nucleic acid sequence in a sample in the presence of at least protein capable of binding to single-stranded DNA is provided, comprising contacting said sample with at least one oligonucleotide probe comprising a fluorophore, a quencher and a region complementary to said target nucleic acid sequence. The sequence of the oligonucleotide probe comprises at least 20% RNA nucleotides, modified RNA nucleotides and/or PNA nucleotides. |
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Bibliography: | Application Number: EP20140800105 |