COMPOSITION OF A NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR

The invention encompasses a composition comprising the reverse transcriptase ("RT") inhibitor 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile sufficiently mixed in a concentration enhancing polymer...

Full description

Saved in:
Bibliographic Details
Main Authors PLOEGER, KRISTIN J. M, TATAVARTI, ADITYA S, LOWINGER, MICHAEL, BLOOM, COREY J, BROOKHART, KATHERINE ANNE, MARSAC, PATRICK JULES
Format Patent
LanguageEnglish
French
German
Published 28.09.2016
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
Online AccessGet full text

Cover

More Information
Summary:The invention encompasses a composition comprising the reverse transcriptase ("RT") inhibitor 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile sufficiently mixed in a concentration enhancing polymer, and processes for making the same. The composition and processes of the present invention significantly improve the bioavailability of the aforementioned RT inhibitor, while maintaining physical stability.
Bibliography:Application Number: EP20140863138