Probiotic lactobacillus strains for use in treating urinary tract infections

• Main Authors: SANTAS GUTIÉRREZ, JONATAN, LÁZARO MALLÉN, ELISABET, CUÑÉ CASTELLANA, JORDI
• Format: Patent
• Language: English; French; German
• Published: 07.09.2016
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The new strains Lactobacillus plantarum CECT8675, CECT8676, CECT8677 and CECT8678 and mutants thereof are provided. The strains present as key advantage that they have the ability to antagonize the urogenital pathogens Staphylococcus saprophyticus, Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis, which are useful in the management of UTI and other related conditions of the urogenital tract. Additionally, the strains of the present invention have the capacity to survive at high concentrations of fosfomycin, antibiotic typically used for managing UTI. In summary, the strains of the present invention can be co-administered with the antibiotic fosfomycin. The present invention also relates to the compositions and products comprising the new strains.