NOVEL CYTOCHROME P450 INHIBITORS AND THEIR METHOD OF USE

Embodiments of the present invention relate to novel cytochrome P450 inhibitors and pharmaceutical compositions thereof having a disease-modifying action in the treatment of diseases associated with the production of cortisol that include metabolic syndrome, obesity, headache, depression, hypertensi...

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Main Authors CHILDERS, WAYNE E, ABOU-GHARBIA, MAGID A, IYER, PRAVIN, BLASS, BENJAMIN ERIC, BORUWA, JOSHODEEP
Format Patent
LanguageEnglish
French
German
Published 20.07.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Embodiments of the present invention relate to novel cytochrome P450 inhibitors and pharmaceutical compositions thereof having a disease-modifying action in the treatment of diseases associated with the production of cortisol that include metabolic syndrome, obesity, headache, depression, hypertension, diabetes mellitus, Cushing's Syndrome, pseudo-Cushing syndrome, cognitive impairment, dementia, heart failure, renal failure, psoriasis, glaucoma, cardiovascular disease, cancer, stroke or incidentalomas.
Bibliography:Application Number: EP20140844491