IL-1 BETA FOR THE PRO-INFLAMMATORY STIMULATION OF A CUTANEOUS SUBSTITUTE OR EXPLANT

• Main Authors: GALLIANO, Marie-Florence, BERNARD, Marine
• Format: Patent
• Language: English; French; German
• Published: 14.10.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to the use of a pro-inflammatory stimulating reagent containing between 10 and 500 ng/mL of interleukin IL-1β to reproduce the physiopathology of atopic dermatitis in vitro and/or to alter the barrier function in a cutaneous substitute or a cutaneous explant. It also re...