METHODS OF REDUCING MICROBIAL CONTAMINATION

• Main Authors: WANG, Danli, SCHOLZ, Matthew T, HOBBS, Terry R
• Format: Patent
• Language: English; French; German
• Published: 16.01.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to an antimicrobial composition for use in delaying the onset of an infection or preventing an infection caused by a microbial organism in an internal cavity of a subject, wherein the antimicrobial composition is to be applied by contacting at least a portion of the interior surface of an opening leading to the internal cavity with an antimicrobial composition; and subsequently at least partially inserting an instrument into the opening, wherein the antimicrobial composition comprises: (i) an effective amount of an antimicrobial component comprising an antiseptic, an antibiotic, or combinations thereof, wherein the antimicrobial component contains more than one antiseptic and one of the antiseptics is a cationic antiseptic; and (ii) a surfactant component distinct from the antimicrobial component, wherein the surfactant component is present in an amount of at least 0.1 wt-% and the surfactant component comprises an anionic surfactant, zwitterionic surfactant, poloxamer surfactant, amine oxide surfactant, or combinations thereof; with the proviso that when the internal cavity comprises a nasal passage, vagina, or oral cavity, the antimicrobial component does not include iodine or chlorhexidine.