METHOD FOR DETERMINING CARDIOVASCULAR DISEASE RISK BY DETERMINING THE LEVEL OF AT LEAST TWO OF THE LIPIDS OF TRIACYLGLYCEROL, CHOLESTEROL ESTERS AND PHOSPHATIDYLETHANOLAMINE

in one aspect., the present Invention provides a method of determining cardiovascular disease (CVD) risk in a subject comprising (a) determining fatty acid composition of lipids In a sample obtained from the subject, wherein the lipids are selected from the group consisting of: (I) triacylgiycerols...

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Bibliographic Details
Main Author MAYR, Manuel
Format Patent
LanguageEnglish
French
German
Published 24.07.2019
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:in one aspect., the present Invention provides a method of determining cardiovascular disease (CVD) risk in a subject comprising (a) determining fatty acid composition of lipids In a sample obtained from the subject, wherein the lipids are selected from the group consisting of: (I) triacylgiycerols (TAGs); and cholesterol esters (CEs); and (b) comparing the fatty acid composition of the lipids in the sample from the subject to a control; wherein a decrease in mean fatty acid chain length in the lipids in the sample from the subject compared to the control indicates an. increased risk of CVD in the subject; and wherein the. CVD is associated with atherosclerotic plaque rupture or thrombosis., and/or the CVD Is an acute ischemic event selected from myocardial infarction, ischemic stroke or sudden cardiac death.
Bibliography:Application Number: EP20140726744