N3 ALKYLATED BENZIMIDAZOLE DERIVATIVE AS MEK INHIBITOR

Pharmaceutical compositions comprising a compound of the formula I selected from 6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and pharmaceutically acceptable salts thereof, for use in the treatment of hyperproliferative diseases, suc...

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Bibliographic Details
Main Authors Hurley, Brian T, Marlow, Allison L, Wallace, Eli M, Lyssikatos, Joseph P
Format Patent
LanguageEnglish
French
German
Published 19.07.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Pharmaceutical compositions comprising a compound of the formula I selected from 6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and pharmaceutically acceptable salts thereof, for use in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals.
Bibliography:Application Number: EP20150177189