NOVEL VACCINE COMPOSITIONS COMPRISING IMMUNOSTIMULATORY OLIGONUCLEOTIDES

The invention provides a vaccine composition comprising an antigen component and an adjuvant component, wherein the adjuvant component comprises a P-class immunostimulatory oligonucleotide and either a combination of a saponin and a sterol; or an oily phase comprising an oil and, optionally, one or...

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Main Authors DOMINOWSKI, PAUL, JOSEPH, MWANGI, DUNCAN, KREBS, RICHARD, LEE, RAI, SHARATH, K, SLY, LAUREL, MARY, FOSS, DENNIS, L, COOK, COREY, PATRICK
Format Patent
LanguageEnglish
French
German
Published 23.03.2016
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Summary:The invention provides a vaccine composition comprising an antigen component and an adjuvant component, wherein the adjuvant component comprises a P-class immunostimulatory oligonucleotide and either a combination of a saponin and a sterol; or an oily phase comprising an oil and, optionally, one or more emulsifiers, said oily phase comprising 2-20% v/v of the vaccine composition, wherein said antigen component is an EHV antigen or a Leishmania antigen.
Bibliography:Application Number: EP20140729191