INDOLE COMPOUNDS THAT ACTIVATE AMPK

The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, o...

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Bibliographic Details
Main Authors SMITH, AARON, CHRISTOPHER, EDMONDS, DAVID, JAMES, BHATTACHARYA, SAMIT, KUMAR, TU, MEIHUA, MIKE, LEE, ESTHER, CHENG, YIN, FERNANDO, DILINIE, PRASADHINI, KUNG, DANIEL, WEI-SHUNG, FILIPSKI, KEVIN, JAMES, CAMERON, KIMBERLY, O'KEEFE, DOWLING, MATTHEW, SCOTT, EBNER, DAVID, CHRISTOPHER
Format Patent
LanguageEnglish
French
German
Published 20.01.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.
Bibliography:Application Number: EP20130801781