USE OF SPACER ELEMENTS IN A NUCLEIC ACID TO CONTROL MOVEMENT OF A HELICASE

The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.

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Bibliographic Details
Main Authors HALL, GRAHAM, WHITE, JAMES, HERON, ANDREW JOHN, CRAWFORD, MARION LOUISE, TURNER, DANIEL JOHN, CLARKE, JAMES, GARALDE, DANIEL RYAN, ALVES, DAVID ANTONI
Format Patent
LanguageEnglish
French
German
Published 13.01.2016
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.
Bibliography:Application Number: EP20140702643