AN IMPROVED PROCESS FOR PREPARATION OF SUGAMMADEX SODIUM

The present invention provides a process for the preparation of sugammadex sodium involving the step of: reacting 6-perdeoxy-6-per-halo-gamma-cyclodextrin with 3-mercapto propionic acid in the presence of alkali metal alkoxide in an organic solvents. The invention also provides a process for purifyi...

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Bibliographic Details
Main Authors GURUSWAMY, Batthini, RAVI, Ponnaiah, RAVIKANTH, Sribhashyam, RAO, Uppala Manikya, NEELA, Praveenkumar
Format Patent
LanguageEnglish
French
German
Published 30.09.2020
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:The present invention provides a process for the preparation of sugammadex sodium involving the step of: reacting 6-perdeoxy-6-per-halo-gamma-cyclodextrin with 3-mercapto propionic acid in the presence of alkali metal alkoxide in an organic solvents. The invention also provides a process for purifying the sugammadex or its pharmaceutically acceptable salts using water and organic solvents.
Bibliography:Application Number: EP20130739511