PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY

The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

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Bibliographic Details
Main Authors SHAH, NAVNIT HARGOVINDAS, ZHANG, YU-E, SANDHU, HARPREET K, MATCHETT, MICHAEL ALLEN, LOMUSCIO, STEVE, MA, HUA
Format Patent
LanguageEnglish
French
German
Published 02.12.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.
Bibliography:Application Number: EP20140701504