ANTI-NOTCH3 ANTIBODIES

Monoclonal antibodies that bind and inhibit activation of human Notch3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of Notch3.

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Bibliographic Details
Main Authors KREUTER, Kelly, ABBOTT, Sandra, TISSIRE, Hamid, PERINO, Samantha, GYURIS, Jeno, WINSTON, William, M., Jr, OKAMURA, Heidi, BELL, Alisa, C, O'HAGAN, Ronan
Format Patent
LanguageEnglish
French
German
Published 24.04.2019
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Monoclonal antibodies that bind and inhibit activation of human Notch3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of Notch3.
Bibliography:Application Number: EP20130818154