IGFBP7 for diagnosing diastolic dysfunction

The present invention relates to a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method comprises measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally,...

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Bibliographic Details
Main Authors BRAZ, JULIAN, KAISER, EDELGARD, BLOCK, DIRK, WIENHUES-THELEN, URSULA-HENRIKE, JANUZZI, JAMES, ZAUGG, CHRISTIAN, BRUNNER, HANS-PETER, KARL, JOHANN, ZIEGLER, ANDRÉ, DIETERLE, THOMAS
Format Patent
LanguageEnglish
French
German
Published 30.09.2015
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The present invention relates to a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method comprises measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally, the level of at least one further marker in a patient suffering from heart failure, and comparing the level to a reference level. Further envisaged is a method of monitoring diastolic function in a patient suffering from heart failure. Also encompassed by the present invention are kits and devices adapted to carry out the method of the present invention.
Bibliography:Application Number: EP20140161732