THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS

The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...

Full description

Saved in:
Bibliographic Details
Main Authors SÁNCHEZ-QUESADA, Jorge, MEDINA PADILLA, Miguel, DE CRISTOBAL BLANCO, Javier, PALOMO NICOLAU, Francisco, PÉREZ DE LA CRUZ MORENO, María Ángeles, MARTÍNEZ MONTERO, Olga, HERRERO SANTOS, Susana, RODRÍGUEZ SALGUERO, Beatriz, DOMÍNGUEZ CORREA, Juan Manuel, FUERTES HUERTA, Ana, LÓPEZ OGALLA, Javier
Format Patent
LanguageEnglish
French
German
Published 12.04.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.
Bibliography:Application Number: EP20130705492