Industrial process for the preparation of buprenorphine and its intermediates

There is provided an efficient industrial process for the preparation of 21-cyclopropyl-7a-(2-hydroxy-3,3-dimethyl-2-butyl)-6,14-endo-ethano-6,7,8,14-tetrahydro-oripavine,i.e. buprenorphine of Formula- I in high yield and purity, with enhanced safety and eco-friendly norms. The invention further rel...

Full description

Saved in:
Bibliographic Details
Main Authors Saxena, Kunal, Sata, Kaushik Babubhai, Saxena, Navin Satyapal
Format Patent
LanguageEnglish
French
German
Published 11.07.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:There is provided an efficient industrial process for the preparation of 21-cyclopropyl-7a-(2-hydroxy-3,3-dimethyl-2-butyl)-6,14-endo-ethano-6,7,8,14-tetrahydro-oripavine,i.e. buprenorphine of Formula- I in high yield and purity, with enhanced safety and eco-friendly norms. The invention further relates to an improved process for preparation of intermediates thereof in high yield and purity.
Bibliography:Application Number: EP20140150077