SYNTHESIS OF RALTEGRAVIR
The present invention relates to a novel synthetic route for the preparation of raltegravir and pharmaceutically acceptable salts, starting from 2-amino-2-methylpropanenitrile and oxadiazole carbonyl chloride, through the formation of a pyrimidinone intermediate of formula (V).
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Main Authors | , , , , , , |
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Format | Patent |
Language | English French German |
Published |
12.08.2015
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a novel synthetic route for the preparation of raltegravir and pharmaceutically acceptable salts, starting from 2-amino-2-methylpropanenitrile and oxadiazole carbonyl chloride, through the formation of a pyrimidinone intermediate of formula (V). |
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Bibliography: | Application Number: EP20120862643 |