Precursors and process for the production of 18F-labelled amino acids

The invention relates to precursors for the production of optically active 18 F-labelled amino acids bearing the radiochemical label on an aromatic ring, in particular 6-[ 18 F]Fluoro-3,4-dihydroxy-L-phenylalanine ([ 18 F]F-L-DOPA) as well as meta- and para-[ 18 F]Fluoro-L-tyrosine. Further, it rela...

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Bibliographic Details
Main Authors HOEPPING, ALEXANDER, MÜLLER, MARCO, MOLLITOR, JAN, SMITS, RENÉ, BAUMGART, DIANA, CLAUSNITZER, ANDREAS
Format Patent
LanguageEnglish
French
German
Published 25.06.2014
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to precursors for the production of optically active 18 F-labelled amino acids bearing the radiochemical label on an aromatic ring, in particular 6-[ 18 F]Fluoro-3,4-dihydroxy-L-phenylalanine ([ 18 F]F-L-DOPA) as well as meta- and para-[ 18 F]Fluoro-L-tyrosine. Further, it relates to a radiochemical method for the production of the corresponding radiotracers.
Bibliography:Application Number: EP20120199109