TREATMENT OF FIBROSIS USING MICRORNA-19B

The present invention provides a method for treating or preventing fibrosis comprising administering to a patient in need of such treatment or prevention an amount of microRNA-19b effective to treat or prevent said fibrosis. In some embodiments, the invention relates to inhibiting the activation of...

Full description

Saved in:
Bibliographic Details
Main Authors LAKNER, ASHLEY, M, SCHRUM, LAURA, W
Format Patent
LanguageEnglish
French
German
Published 11.06.2014
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:The present invention provides a method for treating or preventing fibrosis comprising administering to a patient in need of such treatment or prevention an amount of microRNA-19b effective to treat or prevent said fibrosis. In some embodiments, the invention relates to inhibiting the activation of collagen-producing cells and thereby treating or preventing fibrosis. The methods of the invention also include detection of biomarkers that can be used to diagnose disease and/or evaluate the prognosis of a patient suffering from fibrosis or at risk of developing fibrosis, such as hepatic fibrosis. Such methods may be used to characterize the progression of diseases associated with fibrosis.
Bibliography:Application Number: EP20120748096