COMBINATION OF PANOBINOSTAT AND RUXOLITINIB IN THE TREATMENT OF CANCER SUCH AS A MYELOPROLIFERATIVE NEOPLASM

• Main Authors: BAFFERT, FABIENNE, GADBAW, BRIAN, RADIMERSKI, THOMAS
• Format: Patent
• Language: English; French; German
• Published: 25.05.2016
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention relates to a combination which comprises: (a) Compound A ((R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile) of Formula (A): or a pharmaceutically acceptable salt thereof; and (b) Compound B (N-hydroxy-3-[4-[[[2-(2-methy-1H-indol-3-yl)-ethyl]-amino...