PROCESS FOR CONTINUOUS FLOW SYNTHESIS OF BETA-AMINO CROTONATE

Beta aminocrotonates are important intermediates for the synthesis of Ca channel blockers. The processes available in the art are batch processes with yields about 85%. There are no continuous processes available for the synthesis of such compounds. This gap in the art is addressed by the invention...

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Bibliographic Details
Main Authors JOSHI, Ramesh, Anna, KULKARNI, Amol, Arvind, JOSHI, Rohini, Ramesh
Format Patent
LanguageEnglish
French
German
Published 07.03.2018
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:Beta aminocrotonates are important intermediates for the synthesis of Ca channel blockers. The processes available in the art are batch processes with yields about 85%. There are no continuous processes available for the synthesis of such compounds. This gap in the art is addressed by the invention by disclosing a continuous process resulting in high yields of beta amino crotonates.
Bibliography:Application Number: EP20120729240