METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES

Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates...

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Main Authors DAI, DANMEI, BRUNNER, ANDREAS, DIXON, RACHEL, ANNE, BAARS, SYLVIA, MYRNA, LITTLE, GILLIAN, MARY, LONG, XIANGTIAN, PROISY, NICOLAS, GEORGES, RENE, CLINCH, KEITH, WATT, DEREK, KEVIN, LANDREAU, CYRILLE, ABEL, SÉBASTIEN
Format Patent
LanguageEnglish
French
German
Published 20.08.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.
Bibliography:Application Number: EP20120747519