PREPARATION METHOD OF ROCURONIUM

A method for preparing rocuronium is disclosed. 2²-(4-Morpholinyl)-16²-(1-pyrrolidinyl)-5±-androstan-3±-ol-17²-acetate is used as a starting material and is directly reacted with 3-bromopropene at ambient temperature to produce rocuronium.

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Bibliographic Details
Main Authors ZENG, ZHIWEN, ZHANG, XINI, WANG, PENG, ZHANG, WENLING
Format Patent
LanguageEnglish
French
German
Published 04.12.2013
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:A method for preparing rocuronium is disclosed. 2²-(4-Morpholinyl)-16²-(1-pyrrolidinyl)-5±-androstan-3±-ol-17²-acetate is used as a starting material and is directly reacted with 3-bromopropene at ambient temperature to produce rocuronium.
Bibliography:Application Number: EP20110856787